Publications
Eric Kmiec, Ph.D., Named Editor-in-Chief
Eric Kmiec, Ph.D., executive director and chief scientific officer of ChristianaCare’s Gene Editing Institute, has been selected as editor-in-chief of the scientific journal Gene and Genome Editing. Kmiec served three years on the journal’s board prior to this new position.
2022
Homology directed correction, a new pathway model for point mutation repair catalyzed by CRISPR-Cas
Authors: Sansbury BM, Hewes AM, Tharp OM, Masciarelli SB, Kaouser S, Kmiec EB
Journal: Nature, Scientific Reports, 2022
Exon skipping induced by CRISPR-directed gene editing regulates the response to chemotherapy in non-small cell lung carcinoma cells
Authors: Banas K, Modarai S, Rivera-Torres N, Yoo B-C, Bialk P, Barrett C, Batish M, Kmiec EB
Journal: Gene Therapy, 2022
2021
A toolmaker’s perspective on CRISPR-directed gene editing as a therapeutic strategy for leukemia and beyond
Authors: Kmiec EB, Bloh K
Journal: Expert Reviews in Hematology, 2021
A Consensus Model of Homology-Directed Repair Initiated by CRISPR/Cas Activity
Authors: Bloh K, Rivera-Torres N
Journal: International Journal of Molecular Sciences, 2021
On the Origins of Homology Directed Repair in Mammalian Cells
Authors: Sansbury S, Kmiec EB
Journal: International Journal of Molecular Sciences, 2021
A complete methodology for the instruction of CRISPR-based gene editing using a simplified cell-free extract system with genetic readout in bacteria
Authors: Pisarcik K, Sansbury BM, Kmiec EB
Journal: CRISPR-Cas Methods. Springer Protocols Handbooks, 2021
Deconvolution of complex DNA repair DECODR: Establishing a novel deconvolution algorithm for comprehensive analysis of CRISPR-edited Sanger sequencing data
Authors: Bloh K, Kanchana R, Bialk P, Zhang Z, Yoo, B-C, Kmiec EB
Journal: CRISPR Journal, 2021
Precise and error-prone CRISPR-directed gene editing activity in human CD34+ cells varies widely among patient samples.
Authors: Modarai S, Kanda S, Bloh K, Opdenaker L, Kmiec EB
Journal: Gene Therapy, 2021
2020
The diversity of genetic outcomes from CRISPR/Cas gene editing is regulated by the length of the symmetrical donor DNA template
Authors: Hewes AM, Sansbury BM, Kmiec EB
Journal: Genes (Tenth Anniversary Issue), 2020
Modeling pediatric AML FLT3 mutations using CRISPR/Cas12a- mediated gene editing
Authors: Rivera-Torres N, Banas K, Kmiec EB
Journal: Leukemia & Lymphoma, 2020
Potential Inequities in New Medical Technologies
Authors: Kmiec EB, Marron J
Journal: Scientific American, 2020